KIYAMA, Ryuichi: search on Z-Library

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1

Novel Angiotensin II Receptor Antagonists. Design, Synthesis, and in Vitro Evaluation of Dibenzo[a,d]cycloheptene and Dibenzo[b,f]oxepin Derivatives. Searching for Bioisosteres of Biphenyltetrazole Using a Three-Dimensional Search Technique

Kiyama, Ryuichi, Honma, Tsunetoshi, Hayashi, Kunio, Ogawa, Masayoshi, Hara, Mariko, Fujimoto, Masafumi, Fujishita, Toshio

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.56 MB

english, 1995

2

Marked regression of liver metastasis by combined therapy of ultrasound-mediated NFkB-decoy transfer and transportal injection of paclitaxel, in mouse

Haruhito Azuma, Naruya Tomita, Takeshi Sakamoto, Satoshi Kiyama, Teruo Inamoto, Kiyoshi Takahara, Yatsugu Kotake, Naoki Segawa, Ryuichi Morishita, Shiro Takahara, Hana Hayasaki, Yoshinori Otsuki, Shig

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 845 KB

english, 2008

3

Flexibly crown ether-capped β-cyclodextrin

Ikuo Fujii, Ryuichi Kiyama, Ken Kanematsu

Journal:

Bioorganic Chemistry

Year:

1989

Language:

english

File:

PDF, 225 KB

english, 1989

4

Kinetic studies on the interaction of nonlabeled antagonists with the angiotensin II receptor

Mariko Hara, Ryuichi Kiyama, Shigeyuki Nakajima, Tomoji Kawabata, Masaru Kawakami, Koichi Ohtani, Koji Itazaki, Toshio Fujishita, Masafumi Fujimoto

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1995

Language:

english

File:

PDF, 600 KB

english, 1995

5

Oxidative resolution with bakers' yeast for large-scale production of chiral 1,2-alkanediols

Tadashi Kometani, Yasufumi Morita, Hidefumi Yoshii, Yoshiharu Kiyama, Ryuichi Matsuno

Journal:

Journal of Fermentation and Bioengineering

Year:

1995

Language:

english

File:

PDF, 570 KB

english, 1995

6

A disintegrin and metalloprotease with thrombospondin type1 motifs (ADAMTS-1) and IL-1 receptor type 1 mRNAs are simultaneously induced in nerve injured motor neurons

Masahiko Sasaki, Sumiko Seo-Kiryu, Ryuichi Kato, Shin-ichi Kita, Hiroshi Kiyama

Journal:

Molecular Brain Research

Year:

2001

Language:

english

File:

PDF, 825 KB

english, 2001

7

Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 2. Bi- and Tricyclic Derivatives Result in Superior Antiviral and Pharmacokinetic Profiles

Kawasuji, Takashi, Johns, Brian A., Yoshida, Hiroshi, Weatherhead, Jason G., Akiyama, Toshiyuki, Taishi, Teruhiko, Taoda, Yoshiyuki, Mikamiyama-Iwata, Minako, Murai, Hitoshi, Kiyama, Ryuichi, Fuji, Ma

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 546 KB

english, 2013

8

Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 1. Molecular Design and Establishment of an Advanced Two-Metal Binding Pharmacophore

Kawasuji, Takashi, Johns, Brian A., Yoshida, Hiroshi, Taishi, Teruhiko, Taoda, Yoshiyuki, Murai, Hitoshi, Kiyama, Ryuichi, Fuji, Masahiro, Yoshinaga, Tomokazu, Seki, Takahiro, Kobayashi, Masanori, Sat

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

9

Synthesis and Evaluation of Novel Pyrazolo(1,5-a)pyrimidine Derivatives as Nonpeptide Angiotensin II Receptor Antagonists.

KIYAMA, Ryuichi, HAYASHI, Kunio, HARA, Mariko, FUJIMOTO, Masafumi, KAWABATA, Tomoji, KAWAKAMI, Masaru, NAKAJIMA, Shigeyuki, FUJISHITA, Toshio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1995

File:

PDF, 846 KB

1995

10

Synthesis and pharmacological properties of ureidomethylcarbamoylphenylketone derivatives. A new potent and subtype-selective nonpeptide CCK-B/gastrin receptor antagonist, S-0509

Sanji Hagishita, Yasushi Murakami, Kaoru Seno, Susumu Kamata, Nobuhiro Haga, Toshiro Konoike, Yasuhiko Kanda, Ryuichi Kiyama, Takeshi Shiota, Yasunobu Ishihara, Michio Ishikawa, Mayumi Shimamura, Koji

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.80 MB

english, 1997

11

Ligand−Protein DataBase: Linking Protein−Ligand Complex Structures to Binding Data

Roche, Olivier, Kiyama, Ryuichi, Brooks, Charles L.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 70 KB

english, 2001

12

Synthesis and Evaluation of Novel Nonpeptide Angiotensin II Receptor Antagonists: Imidazo(4,5-c)pyridine Derivatives with an Aromatic Substituent.

KIYAMA, Ryuichi, FUJI, Masahiro, HARA, Mariko, FUJIMOTO, Masafumi, KAWABATA, Tomoji, NAKAMURA, Masuhisa, FUJISHITA, Toshio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1995

File:

PDF, 1.40 MB

1995

13

A platform for designing HIV integrase inhibitors. Part 2: A two-metal binding model as a potential mechanism of HIV integrase inhibitors

Takashi Kawasuji, Masahiro Fuji, Tomokazu Yoshinaga, Akihiko Sato, Tamio Fujiwara, Ryuichi Kiyama

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 679 KB

english, 2006

14

A platform for designing HIV integrase inhibitors. Part 1: 2-Hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores

Takashi Kawasuji, Tomokazu Yoshinaga, Akihiko Sato, Mitsuaki Yodo, Tamio Fujiwara, Ryuichi Kiyama

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 595 KB

english, 2006

15

Alteration of glial cell line-derived neurotrophic factor family receptor alpha-2 mRNA expression and its co-expression with neuronal nitric oxide synthase in pelvic ganglia following unilateral cavernous nerve injury

Shin-ichi Hisasue, Ryuichi Kato, Ko Kobayashi, Takahiro Suetomi, Hiroshi Kiyama, Taiji Tsukamoto

Journal:

International Journal of Urology

Year:

2008

Language:

english

File:

PDF, 290 KB

english, 2008

16

Relationship between ethanol consumption rate and prochiral ketone reduction rate in bakers' yeast

Tadashi Kometani, Yasufumi Morita, Yoshiharu Kiyama, Hidefumi Yoshii, Ryuichi Matsuno

Journal:

Journal of Fermentation and Bioengineering

Year:

1995

Language:

english

File:

PDF, 270 KB

english, 1995

17

3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as advanced inhibitors of HIV integrase

Takashi Kawasuji, Masahiro Fuji, Tomokazu Yoshinaga, Akihiko Sato, Tamio Fujiwara, Ryuichi Kiyama

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 188 KB

english, 2007

18

Synthesis and structure-activity relationships of dual histamine H2 and gastrin receptor antagonists with noncyclic gastrin receptor antagonistic moieties

Yasuyuki Kawanishi, Shoichi Ishihara, Ryuichi Kiyama, Sanji Hagishita, Tadahiko Tsushima, Michio Ishikawa, Yasunobu Ishihara

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 665 KB

english, 1997

19

Cavernous nerve injury elicits GAP-43 mRNA expression but not regeneration of injured pelvic ganglion neurons

Ryuichi Kato, Sumiko Kiryu-Seo, Yoshikazu Sato, Shinichi Hisasue, Taiji Tsukamoto, Hiroshi Kiyama

Journal:

Year:

2003

Language:

english

File:

PDF, 1.82 MB

english, 2003

20

Homology Modeling of Gelatinase Catalytic Domains and Docking Simulations of Novel Sulfonamide Inhibitors

Kiyama, Ryuichi, Tamura, Yoshinori, Watanabe, Fumihiko, Tsuzuki, Hiroshige, Ohtani, Mitsuaki, Yodo, Mitsuaki

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 302 KB

english, 1999

21

Damage-Induced Neuronal Endopeptidase (DINE/ECEL) Expression Is Regulated by Leukemia Inhibitory Factor and Deprivation of Nerve Growth Factor in Rat Sensory Ganglia after Nerve Injury

Kato, Ryuichi, Kiryu-Seo, Sumiko, Kiyama, Hiroshi

Journal:

Journal of Neuroscience

Year:

2002

File:

PDF, 556 KB

2002

22

Age-related alteration of neurturin receptor GFRa2 and nNOS in pelvic ganglia

Shin-ichi Hisasue, Ryuichi Kato, Takahiro Suetomi, Kazunori Kato, Kazuhiro Suzuki, Ko Kobayashi, Naoki Itoh, Hiroshi Kiyama, Taiji Tsukamoto

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 408 KB

english, 2006

23

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Johns, Brian A., Kawasuji, Takashi, Weatherhead, Jason G., Taishi, Teruhiko, Temelkoff, David P., Yoshida, Hiroshi, Akiyama, Toshiyuki, Taoda, Yoshiyuki, Murai, Hitoshi, Kiyama, Ryuichi, Fuji, Masahir

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

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